Description

4-Pyrimidinecarboxylic Acid, 5-Hydroxy-2-Methyl- is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its unique pyrimidine core functionalized with both carboxylic acid and hydroxyl groups makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and plant growth regulators that require a functionalized pyrimidine scaffold.
• Ligand and Chelator Development: Serves as a precursor for designing specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Investigated as a monomer or additive for creating functional polymers and advanced organic materials.
• Biochemical Research: Employed in the study of enzyme interactions and metabolic pathways involving pyrimidine derivatives.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, high-value heterocyclic compounds.

Basic Information

Item	Detail
Product Name	4-Pyrimidinecarboxylic Acid, 5-Hydroxy-2-Methyl-
CAS No.	1504287-88-0
Molecular Formula	C6H6N2O3
Molecular Weight	154.12 g/mol
Synonyms	5-Hydroxy-2-methylpyrimidine-4-carboxylic acid; 2-Methyl-5-hydroxypyrimidine-4-carboxylic acid; 5-Hydroxy-2-methyl-4-pyrimidinecarboxylic acid; 4-Carboxy-5-hydroxy-2-methylpyrimidine; 2-Methyl-4-carboxy-5-hydroxypyrimidine; 5-Hydroxy-2-methyl-4-carboxypyrimidine
EINECS	Contact for details

Quality Control

Every batch of 4-Pyrimidinecarboxylic Acid, 5-Hydroxy-2-Methyl- is produced and tested under a strict quality management system. We ensure high purity and consistent performance through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.