Description

3-Bromo-2,4-Difluorobenzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic positioning of halogen and fluorine substituents, which enable precise structural modifications and tuning of electronic properties in target molecules. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery, particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the difluoro and bromo groups contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for specialized ligands in catalysis and as a building block for functional materials.
• Fluorine Chemistry Research: An important substrate for studying nucleophilic aromatic substitution (SNAr) and cross-coupling reactions involving halogenated aromatics.
• Liquid Crystal and OLED Material Precursor: Utilized in the synthesis of fluorinated aromatic cores for advanced electronic and display materials.

Basic Information

Product Name	3-Bromo-2,4-Difluorobenzyl Alcohol
CAS No.	1499465-33-6
Molecular Formula	C7H5BrF2O
Molecular Weight	223.02 g/mol
Synonyms	(3-Bromo-2,4-difluorophenyl)methanol; 2,4-Difluoro-3-bromobenzyl Alcohol; 3-Bromo-2,4-difluorobenzenemethanol; 1-(Bromodifluoromethyl)-2-fluorobenzene-3-ol (incorrect but common search variant); Benzyl alcohol, 3-bromo-2,4-difluoro-; BDFBA (abbreviation)
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,4-Difluorobenzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing batch-specific results against agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged operations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.