Description

4-Fluoro-5-Iodo-2-Methoxy-Phenylamine is a high-purity, multi-functional halogenated aniline derivative designed for advanced chemical synthesis. This compound serves as a critical building block in pharmaceutical and agrochemical research, offering unique reactivity due to its strategically positioned fluorine and iodine substituents. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the halogen atoms contribute to biological activity and metabolic stability.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and materials science applications.
• Fluorescent Dye & Sensor Development: Acts as a starting material for synthesizing advanced fluorophores and molecular probes used in bio-imaging and diagnostics.
• Polymer Chemistry: Serves as a monomer or functionalization agent for creating specialty polymers with specific electronic or surface properties.
• Cross-Coupling Reactions: The iodine moiety makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct complex biaryl systems.

Basic Information

Product Name	4-Fluoro-5-Iodo-2-Methoxy-Phenylamine
CAS No.	1483938-10-8
Molecular Formula	C7H7FINO
Molecular Weight	267.04 g/mol
Synonyms	2-Methoxy-4-fluoro-5-iodoaniline; 5-Iodo-4-fluoro-2-methoxyaniline; 4-Fluoro-5-iodo-2-methoxybenzenamine; 2-Amino-5-iodo-4-fluoroanisole; Benzenamine, 4-fluoro-5-iodo-2-methoxy-; 4-Fluoro-5-iodo-o-anisidine
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-5-Iodo-2-Methoxy-Phenylamine is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.