Description

(S,E)-n-(1-((5-(2-((4-Cyanophenyl)Amino)-4-(Propylamino)Pyrimidin-5-Yl)Pent-4-Yn-1-Yl)Amino)-1-Oxopropan-2-Yl)-4-(Dimethylamino)-n-Methylbut-2-Enamide is a high-purity, synthetic organic compound featuring a complex molecular architecture designed for targeted biological activity. This compound is of significant interest for its potential as a key intermediate or active pharmaceutical ingredient (API) in advanced therapeutic research. It is primarily sought by pharmaceutical R&D laboratories and biotechnology companies engaged in the discovery and development of novel small-molecule drugs.

Application

• Pharmaceutical Research & Development: Serves as a critical building block or precursor in the synthesis of novel drug candidates targeting specific enzymes or receptors.
• Kinase Inhibitor Development: Due to its pyrimidine core and structural motifs, it is investigated for use in creating potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Preclinical Studies: Used in in vitro and in vivo studies to evaluate pharmacokinetics, pharmacodynamics, and initial efficacy of new therapeutic entities.
• Chemical Biology Probes: Employed as a tool compound to study and modulate specific biological pathways and protein functions in academic and industrial research settings.
• Process Chemistry & Scale-Up: Acts as a reference standard or starting material for optimizing synthetic routes and scaling up production for clinical trial material.

Basic Information

Product Name	(S,E)-n-(1-((5-(2-((4-Cyanophenyl)Amino)-4-(Propylamino)Pyrimidin-5-Yl)Pent-4-Yn-1-Yl)Amino)-1-Oxopropan-2-Yl)-4-(Dimethylamino)-n-Methylbut-2-Enamide
CAS No.	1472797-69-5
Molecular Formula	C30H38N8O2
Molecular Weight	542.68 g/mol
Synonyms	(S,E)-N-(1-((5-(2-((4-Cyanophenyl)amino)-4-(propylamino)pyrimidin-5-yl)pent-4-yn-1-yl)amino)-1-oxopropan-2-yl)-4-(dimethylamino)-N-methylbut-2-enamide; 1472797-69-5; (S,E)-N-(1-{[5-(2-{[4-Cyanophenyl]amino}-4-{[propyl]amino}pyrimidin-5-yl)pent-4-yn-1-yl]amino}-1-oxopropan-2-yl)-4-(dimethylamino)-N-methylbut-2-enamide; But-2-enamide, (S,E)-N-[1-[[5-[2-[(4-cyanophenyl)amino]-4-(propylamino)-5-pyrimidinyl]-4-pentyn-1-yl]amino]-1-oxo-2-propanyl]-4-(dimethylamino)-N-methyl-; A potential kinase inhibitor intermediate
EINECS	Contact for details

Quality Control

Our production of (S,E)-n-(1-((5-(2-((4-Cyanophenyl)Amino)-4-(Propylamino)Pyrimidin-5-Yl)Pent-4-Yn-1-Yl)Amino)-1-Oxopropan-2-Yl)-4-(Dimethylamino)-n-Methylbut-2-Enamide adheres to stringent quality protocols suitable for research and pharmaceutical development. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This compound is typically moisture-sensitive (hygroscopic); therefore, the container should be kept in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.