Description

8-Methoxypyrido[3,4-D]Pyrimidine-2,4-Diol is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other therapeutic areas. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study biological pathways and protein function.
• Process Chemistry: Employed in route scouting and scale-up synthesis for Active Pharmaceutical Ingredient (API) manufacturing.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.

Basic Information

Item	Detail
Product Name	8-Methoxypyrido[3,4-D]Pyrimidine-2,4-Diol
CAS No.	1470249-15-0
Molecular Formula	C8H7N3O3
Molecular Weight	193.16 g/mol
Synonyms	8-Methoxypyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione; 8-Methoxy-1H,3H-pyrido[3,4-d]pyrimidine-2,4-dione; 2,4-Dihydroxy-8-methoxypyrido[3,4-d]pyrimidine; 8-Methoxy-2,4-dioxo-1,2,3,4-tetrahydropyrido[3,4-d]pyrimidine; 1470249-15-0; Pyrido[3,4-d]pyrimidine-2,4-diol, 8-methoxy-
EINECS	Contact for details

Quality Control

Our 8-Methoxypyrido[3,4-D]Pyrimidine-2,4-Diol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.