Description

Angiostatin K1-5, Human is a recombinant protein fragment known for its potent anti-angiogenic properties, specifically inhibiting the formation of new blood vessels. This makes it a critical research tool and a promising candidate for therapeutic development in oncology and ophthalmology. It is essential for researchers and developers in the biopharmaceutical sector focusing on cancer biology, vascular disorders, and novel anti-cancer drug discovery.

Application

• Biomedical Research: Fundamental studies on angiogenesis, tumor growth, and metastasis mechanisms.
• Drug Discovery & Development: Screening and validation of anti-angiogenic compounds and therapeutic candidates.
• In Vitro & In Vivo Assays: Used as a reference standard or active agent in cell-based and animal model studies.
• Cancer Research: Investigation of tumor microenvironment and development of targeted cancer therapies.
• Ophthalmic Disease Models: Research into conditions like age-related macular degeneration (AMD) and diabetic retinopathy.
• Reagent Production: Component in the formulation of specialized biochemical kits and reagents.

Basic Information

Product Name	Angiostatin K1-5, Human
CAS No.	1469985-12-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Human Angiostatin K1-5; Recombinant Human Angiostatin K1-5; Angiostatin (K1-5); Angiostatin Fragment K1-5; Plasminogen Fragment K1-5; Angiogenesis Inhibitor K1-5; K1-5 Angiostatin
EINECS	Contact for details

Quality Control

Our Angiostatin K1-5, Human is produced and tested under stringent quality systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and biological activity. Certificates of Analysis (COA) detailing specifications such as purity (by SDS-PAGE and HPLC), endotoxin levels, and sterility are provided to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C to -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Corresponds to reference standard
Purity (HPLC)	≥ 95%
Protein Content	Determined by UV absorbance
Endotoxin	< 1.0 EU/µg
Biological Activity	Inhibition of endothelial cell proliferation in vitro
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.