Description

2-(2-Methyl-Cyclopropyl)-Pyrimidine-5-Carboxylic Acid is a high-value pyrimidine carboxylic acid derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique bicyclic structure imparts specific biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its pyrimidine core.
• Ligand & Catalyst Development: Serves as a sophisticated ligand precursor in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of organic electronic materials and advanced polymers due to its conjugated system.
• Chemical Biology Probe: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up services for clients requiring bespoke chemical entities.

Basic Information

Product Name	2-(2-Methyl-Cyclopropyl)-Pyrimidine-5-Carboxylic Acid
CAS No.	1468808-18-5
Molecular Formula	C9H10N2O2
Molecular Weight	178.19 g/mol
Synonyms	5-Pyrimidinecarboxylic acid, 2-(2-methylcyclopropyl)-; 2-(2-Methylcyclopropyl)pyrimidine-5-carboxylic acid; 2-(2-Methyl-cyclopropyl)-pyrimidin-5-carbonsäure (German); Acide 2-(2-méthylcyclopropyl)pyrimidine-5-carboxylique (French); 1468808-18-5; 2-(2-Methylcyclopropyl)-5-pyrimidinecarboxylic acid; 5-Carboxy-2-(2-methylcyclopropyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 2-(2-Methyl-Cyclopropyl)-Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.