Description

4‐Bromo‐3,5‐Difluoro‐2‐Iodoaniline is a high-purity, multi-halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise and reliable halogenated intermediates for their R&D and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for imaging, diagnostics, and biochemical assays.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the presence of bromo and iodo substituents.
• Organic Synthesis Building Block: Provides a versatile aromatic core for further functionalization in complex multi-step synthetic routes.

Basic Information

Product Name	4‐Bromo‐3,5‐Difluoro‐2‐Iodoaniline
CAS No.	1467060-36-1
Molecular Formula	C6H3BrF2IN
Molecular Weight	333.90 g/mol
Synonyms	2-Iodo-4-bromo-3,5-difluoroaniline; 4-Bromo-3,5-difluoro-2-iodobenzenamine; 2-Amino-4-bromo-1,5-difluoro-3-iodobenzene; Benzenamine, 4-bromo-3,5-difluoro-2-iodo-; 1467060-36-1; 4-Br-3,5-F2-2-I-aniline
EINECS	Contact for details

Quality Control

Our 4‐Bromo‐3,5‐Difluoro‐2‐Iodoaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.