Description

5-(3-Chlorophenyl)-3-(2-Oxo-2-Phenylethyl)Pyrazolo[1,5-A]Pyrimidine-2,7(1H,4H)-Dione is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile pyrazolopyrimidine-dione scaffold for creating novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on developing new drug candidates, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Kinase Inhibitor Development: The pyrazolopyrimidine core is a privileged structure in the design of kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological processes and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and methodology development.

Basic Information

Product Name	5-(3-Chlorophenyl)-3-(2-Oxo-2-Phenylethyl)Pyrazolo[1,5-A]Pyrimidine-2,7(1H,4H)-Dione
CAS No.	1464091-52-8
Molecular Formula	C20H14ClN3O3
Molecular Weight	379.80 g/mol
Synonyms	5-(3-Chlorophenyl)-3-(2-oxo-2-phenylethyl)-1H,4H-pyrazolo[1,5-a]pyrimidine-2,7-dione; 5-(3-Chlorophenyl)-3-(phenacyl)pyrazolo[1,5-a]pyrimidine-2,7-dione; CAS 1464091-52-8; Pyrazolo[1,5-a]pyrimidine-2,7-dione, 5-(3-chlorophenyl)-3-(2-oxo-2-phenylethyl)-1,4-dihydro-; 1,4-Dihydro-5-(3-chlorophenyl)-3-(2-oxo-2-phenylethyl)pyrazolo[1,5-a]pyrimidine-2,7-dione
EINECS	Contact for details

Quality Control

Our 5-(3-Chlorophenyl)-3-(2-Oxo-2-Phenylethyl)Pyrazolo[1,5-A]Pyrimidine-2,7(1H,4H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.