Description

n-(5-Cyclopropyl-2,7-Dioxo-1,2,4,7-Tetrahydropyrazolo[1,5-A]Pyrimidin-3-Yl)Benzamide CAS NO 1464091-42-6 is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of investigational new drugs (INDs) and potential APIs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Kinase Inhibitor Development: The pyrazolopyrimidine core is a privileged structure in the design of kinase inhibitors for oncology and inflammatory diseases.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Biochemical Research: May be utilized as a tool compound or ligand in biochemical assays to study protein-ligand interactions.

Basic Information

Product Name	n-(5-Cyclopropyl-2,7-Dioxo-1,2,4,7-Tetrahydropyrazolo[1,5-A]Pyrimidin-3-Yl)Benzamide
CAS No.	1464091-42-6
Molecular Formula	C₁₇H₁₄N₄O₃
Molecular Weight	322.32 g/mol
Synonyms	3-Benzamido-5-cyclopropyl-1,2-dihydropyrazolo[1,5-a]pyrimidine-2,7-dione; Benzamide, N-[5-cyclopropyl-2,7-dioxo-1,2,4,7-tetrahydro-1H-pyrazolo[1,5-a]pyrimidin-3-yl]-; 1464091-42-6; 5-Cyclopropyl-3-(benzoylamino)-1H-pyrazolo[1,5-a]pyrimidine-2,7-dione; 5-Cyclopropyl-3-[(phenylcarbonyl)amino]-1,2-dihydro-2,7-dioxopyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our n-(5-Cyclopropyl-2,7-Dioxo-1,2,4,7-Tetrahydropyrazolo[1,5-A]Pyrimidin-3-Yl)Benzamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), related substances, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.