Description

2-Bromo-5-Fluoro-3-Methylaniline is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized aromatic core with multiple reactive sites, enabling the construction of complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing halogenated aniline motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bromo and fluoro substituents enhance biological activity and stability.
• Material Science Research: Employed as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing complex azo dyes and high-performance pigments.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed reactions like Suzuki, Buchwald-Hartwig, and Ullmann couplings for C-N and C-C bond formation.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical and diagnostic applications.

Basic Information

Product Name	2-Bromo-5-Fluoro-3-Methylaniline
CAS No.	1463053-93-1
Molecular Formula	C7H7BrFN
Molecular Weight	204.04 g/mol
Synonyms	2-Bromo-5-fluoro-3-methylbenzenamine; 3-Amino-2-bromo-5-fluorotoluene; 2-Bromo-5-fluoro-m-toluidine; Benzenamine, 2-bromo-5-fluoro-3-methyl-; 3-Methyl-2-bromo-5-fluoroaniline; 5-Fluoro-2-bromo-3-methylaniline; 2-Bromo-5-fluoro-3-methyl-phenylamine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Fluoro-3-Methylaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.