Description

4-Chloro-n-(1-Methyl-1H-Pyrazol-4-Yl)Pyrimidin-2-Amine CAS NO 1462286-01-6 is a high-purity, heterocyclic organic compound featuring a pyrimidine core substituted with a chloro group and a 1-methyl-1H-pyrazol-4-yl amine moiety. This specific molecular architecture makes it a valuable and versatile pharmaceutical intermediate and research chemical for the development of novel active ingredients. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and life science sectors seeking to synthesize and evaluate new chemical entities for therapeutic applications.

Application

This specialized chemical building block is designed for advanced synthetic applications. Its primary and potential uses include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential kinase inhibitors and other targeted small-molecule therapeutics.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Chemical Biology Probe: Serves as a scaffold for creating molecular tools to study biological pathways and protein function.
• Medicinal Chemistry R&D: Employed in lead optimization and structure-activity relationship (SAR) studies during drug discovery campaigns.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for clients.
• Academic Research: Used in university and institutional labs for fundamental studies in heterocyclic chemistry and synthetic methodology.

Basic Information

Product Name	4-Chloro-n-(1-Methyl-1H-Pyrazol-4-Yl)Pyrimidin-2-Amine
CAS No.	1462286-01-6
Molecular Formula	C8H9ClN5
Molecular Weight	210.64 g/mol
Synonyms	4-Chloro-N-(1-methyl-1H-pyrazol-4-yl)pyrimidin-2-amine; 2-Pyrimidinamine, 4-chloro-N-(1-methyl-1H-pyrazol-4-yl)-; 4-Chloro-2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidine; N-(1-Methyl-1H-pyrazol-4-yl)-4-chloropyrimidin-2-amine; 4-Chloro-N-(1-methylpyrazol-4-yl)pyrimidin-2-amine; 1462286-01-6; A-2058040; AKOS040750184
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-n-(1-Methyl-1H-Pyrazol-4-Yl)Pyrimidin-2-Amine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.