Description

(9H-Fluoren-9-Yl)Methoxy]Carbonyl Thr(Tbu)-Gly-Oh is a protected dipeptide building block, specifically Fmoc-Thr(tBu)-Gly-OH, which is essential for the solid-phase synthesis of complex peptides and proteins. This compound matters because it provides critical orthogonality and stability during peptide chain assembly, enabling the precise construction of biologically active sequences. Pharmaceutical researchers and fine chemical manufacturers need it for the development of therapeutic peptides, diagnostic agents, and advanced biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the automated, sequential assembly of peptide chains using Fmoc-chemistry protocols.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based therapeutics, including hormone analogs and enzyme inhibitors.
• Bioconjugation: Serves as a building block for creating peptide-drug conjugates or peptide-labeled probes for targeted delivery and diagnostics.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify new bioactive compounds.
• Academic & Industrial R&D: Fundamental reagent for studying protein structure-function relationships and developing new synthetic methodologies.
• Production of Custom Peptides: Essential for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptides for clients.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methoxy]Carbonyl Thr(Tbu)-Gly-Oh
CAS No.	1456878-79-7
Molecular Formula	C26H30N2O6
Molecular Weight	466.53 g/mol
Synonyms	Fmoc-Thr(tBu)-Gly-OH; Fmoc-O-tert-butylthreonyl-glycine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(tert-butyl)-L-threonylglycine; Fmoc-L-Thr(tBu)-Gly-OH; Nα-Fmoc-O-tert-butyl-L-threonylglycine; (2S,3R)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-[(2-methylpropan-2-yl)oxy]butanoylglycine; Fmoc-Thr(OtBu)-Gly-OH; Protected Fmoc-Thr-Gly dipeptide
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methoxy]Carbonyl Thr(Tbu)-Gly-Oh is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.