Description

Di-Fmoc-Dl-Cystathionine is a protected derivative of the sulfur-containing amino acid cystathionine, featuring two fluorenylmethyloxycarbonyl (Fmoc) protecting groups. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of cystathionine into complex peptide chains. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers developing novel peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid derivative, it serves as a key intermediate for the automated synthesis of peptides containing the cystathionine moiety.
• Pharmaceutical Research: Used in the development and production of peptide drugs targeting metabolic pathways, cardiovascular diseases, and neurological disorders where cystathionine plays a role.
• Biochemical Research: Employed as a precursor or standard in studies related to transsulfuration pathways, homocysteine metabolism, and sulfur amino acid biology.
• Production of Custom Peptides: Essential for contract research organizations (CROs) and CDMOs offering bespoke peptide synthesis services for clients in academia and industry.
• Proteomics and Biomarker Development: Can be used to synthesize peptide sequences for use as antigens, enzyme substrates, or internal standards in mass spectrometry.

Basic Information

Product Name	Di-Fmoc-Dl-Cystathionine
CAS No.	1452573-76-0
Molecular Formula	C33H34N2O8S
Molecular Weight	618.70 g/mol
Synonyms	Bis-Fmoc-DL-Cystathionine; N,N-Bis(9-fluorenylmethoxycarbonyl)-DL-cystathionine; DL-Cystathionine, N,N-bis(9H-fluoren-9-ylmethoxy)carbonyl]-; Fmoc-Cystathionine(Fmoc)-OH; (2R)-2,2'-{[(2S)-2-Amino-2-carboxyethyl]sulfanediyl}bis(2-aminoacetic acid) bis(9H-fluoren-9-ylmethyl) ester; Cystathionine, N,N-di-Fmoc-; DI-FMOC-CYSTAT; Protected Cystathionine derivative
EINECS	Contact for details

Quality Control

Our Di-Fmoc-Dl-Cystathionine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the high-purity standards required for sensitive peptide synthesis applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.