Description

4-((3-Chloro-4-Methoxybenzyl)Amino)-2-Hydroxy-n-(Pyrimidin-2-Ylmethyl)Pyrimidine-5-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for precision synthesis. This compound is critical for research and development in medicinal chemistry, particularly in the creation of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting kinase inhibition and other specialized biological pathways.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Research: Serves as a core scaffold for developing potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Assay Development: Employed as a reference standard or probe compound in high-throughput screening (HTS) and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for fundamental research in chemical biology and drug discovery.

Basic Information

Product Name	4-((3-Chloro-4-Methoxybenzyl)Amino)-2-Hydroxy-n-(Pyrimidin-2-Ylmethyl)Pyrimidine-5-Carboxamide
CAS No.	1452128-53-8
Molecular Formula	C18H18ClN7O3
Molecular Weight	415.83 g/mol
Synonyms	4-[(3-Chloro-4-methoxybenzyl)amino]-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide; 2-Hydroxy-4-((3-chloro-4-methoxybenzyl)amino)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide; UNII-9V2I9Q2K1F; 9V2I9Q2K1F; 1452128-53-8; 4-((3-Chloro-4-methoxybenzyl)amino)-2-hydroxy-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide; 4-[(3-Chloro-4-methoxybenzyl)amino]-2-hydroxy-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide
EINECS	Contact for details

Quality Control

Our 4-((3-Chloro-4-Methoxybenzyl)Amino)-2-Hydroxy-n-(Pyrimidin-2-Ylmethyl)Pyrimidine-5-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); handle and store under inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.