Description

5,6-Dimethyl-N4-(2-Methylphenyl)-N2-(Pyridin-2-Ylmethyl)Pyrimidine-2,4-Diamine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel therapeutic agents. This compound is critical for research and development in medicinal chemistry, offering a sophisticated building block for creating targeted drug candidates. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic entities.
• Kinase Inhibitor Development: Serves as a core scaffold for the design and synthesis of potential kinase inhibitors due to its pyrimidine-diamine structure.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for exploratory research in heterocyclic and organic synthesis.
• High-Value Fine Chemical Production: Integrated into multi-step synthetic routes for the manufacture of complex, high-value specialty chemicals.

Basic Information

Product Name	5,6-Dimethyl-N4-(2-Methylphenyl)-N2-(Pyridin-2-Ylmethyl)Pyrimidine-2,4-Diamine
CAS No.	1450809-59-2
Molecular Formula	C20H23N5
Molecular Weight	333.44 g/mol
Synonyms	5,6-Dimethyl-N2-[(2-pyridinyl)methyl]-N4-(2-methylphenyl)-2,4-pyrimidinediamine; N4-(2-Methylphenyl)-N2-(pyridin-2-ylmethyl)-5,6-dimethylpyrimidine-2,4-diamine; 2,4-Pyrimidinediamine, 5,6-dimethyl-N2-[(2-pyridinyl)methyl]-N4-(2-methylphenyl)-; 1450809-59-2; 5,6-Dimethyl-N4-o-tolyl-N2-(pyridin-2-ylmethyl)pyrimidine-2,4-diamine
EINECS	Contact for details

Quality Control

Our 5,6-Dimethyl-N4-(2-Methylphenyl)-N2-(Pyridin-2-Ylmethyl)Pyrimidine-2,4-Diamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.