Description

Glycine, 1-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Prolylglycylglycylglycyl- is a specialized, high-purity peptide derivative used as a critical building block in advanced chemical synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel peptide-based therapeutics and biochemical tools. Its primary value lies in enabling the controlled assembly of complex peptide chains, making it indispensable for pharmaceutical R&D, proteomics, and advanced materials science.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid derivative for the sequential construction of custom peptides and peptidomimetics.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the research and development of new peptide drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation & Labeling: Used in the site-specific modification of proteins and other biomolecules for diagnostic and therapeutic applications.
• Biochemical Research: Employed as a standard or reagent in proteomics, enzyme studies, and structure-activity relationship (SAR) investigations.
• Ligand Development: Facilitates the creation of specific peptide ligands for targeting receptors in drug discovery programs.
• Material Science: A component in the synthesis of peptide-based polymers and smart biomaterials.

Basic Information

Product Name	Glycine, 1-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Prolylglycylglycylglycyl-
CAS No.	1450625-21-4
Molecular Formula	C31H35N5O8
Molecular Weight	605.64 g/mol
Synonyms	Fmoc-L-Prolylglycylglycylglycine; Fmoc-Pro-Gly-Gly-Gly-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolylglycylglycylglycine; Fmoc-Pro-Gly3-OH; 1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-prolylglycylglycylglycine; Fmoc-PGGG-OH; Nα-Fmoc-L-prolylglycylglycylglycine
EINECS	Contact for details

Quality Control

Every batch of Glycine, 1-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-L-Prolylglycylglycylglycyl- is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.