Description

2-Chloro-7-Fluoro-4H-Pyrido[1,2-A]Pyrimidin-4-One is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers focused on developing new fluorinated and chlorinated heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its fluorinated pyrimidine core.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme inhibition and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique electronic or optical properties.
• Academic & Contract Research: Essential for synthetic organic chemistry research in academic institutions and CROs (Contract Research Organizations).

Basic Information

Product Name	2-Chloro-7-Fluoro-4H-Pyrido[1,2-A]Pyrimidin-4-One
CAS No.	1449598-86-0
Molecular Formula	C8H3ClFN2O
Molecular Weight	196.57 g/mol
Synonyms	2-Chloro-7-fluoropyrido[1,2-a]pyrimidin-4-one; 2-Chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one; 1449598-86-0; 2-Chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one; Pyrido[1,2-a]pyrimidin-4-one, 2-chloro-7-fluoro-; SCHEMBL23383077; AKOS040759623; FT-0776927
EINECS	Contact for details

Quality Control

Our 2-Chloro-7-Fluoro-4H-Pyrido[1,2-A]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.