Description

7-Fluoro-2-Hydroxy-4H-Pyrido[1,2-A]Pyrimidin-4-One is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique pyridopyrimidinone scaffold, which serves as a critical intermediate for developing novel pharmacologically active compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create new molecules with potential therapeutic and biological activity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging the biological activity of the fluorinated pyridopyrimidinone structure.
• Chemical Biology Probe Development: Serves as a core scaffold for creating molecular probes to study enzyme function and biological pathways in academic and industrial research settings.
• Material Science Precursor: Potential use as a specialty monomer or precursor for synthesizing advanced organic materials with specific electronic or photophysical properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical and agrochemical companies in their discovery and development pipelines.

Basic Information

Product Name	7-Fluoro-2-Hydroxy-4H-Pyrido[1,2-A]Pyrimidin-4-One
CAS No.	1449598-85-9
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	7-Fluoro-2-hydroxy-4H-pyrido[1,2-a]pyrimidin-4-one; 4H-Pyrido[1,2-a]pyrimidin-4-one, 7-fluoro-2-hydroxy-; 7-Fluoro-2-hydroxypyrido[1,2-a]pyrimidin-4-one; 1449598-85-9; FC-2345 (Potential Research Code); 7-F-2-HPPO (Abbreviation); 2-Hydroxy-7-fluoropyrido[1,2-a]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 7-Fluoro-2-Hydroxy-4H-Pyrido[1,2-A]Pyrimidin-4-One is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.