Description

4-Fluoro-3-(Methylthio)Benzyl Alcohol is a versatile fluorinated aromatic building block with a reactive benzylic hydroxyl group. This compound matters for its role in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the fluorine and methylthio substituents can significantly influence biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity and target binding.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Synthesis Building Block: Employed in Suzuki, Heck, and other cross-coupling reactions to introduce the substituted benzyl moiety into complex molecular architectures.
• Chemical Research & Development: Utilized in academic and industrial labs for method development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	4-Fluoro-3-(Methylthio)Benzyl Alcohol
CAS No.	1449008-21-2
Molecular Formula	C8H9FOS
Molecular Weight	172.22 g/mol
Synonyms	(4-Fluoro-3-methylsulfanylphenyl)methanol; 3-(Methylthio)-4-fluorobenzyl Alcohol; 4-Fluoro-3-(methylmercapto)benzyl Alcohol; 1-(4-Fluoro-3-(methylthio)phenyl)methanol; α-Hydroxymethyl-4-fluoro-3-methylthiobenzene; 4-Fluoro-3-methylthiobenzyl Alcohol; Benzenemethanol, 4-fluoro-3-(methylthio)-
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(Methylthio)Benzyl Alcohol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.