Description

2-Chloro-4-Fluoro-6-Phenylaniline is a high-purity, halogenated aniline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional agrochemicals, where its unique substitution pattern enables precise molecular design. Industries requiring sophisticated fine chemical synthesis, including pharmaceutical R&D, agrochemical manufacturing, and specialty material science, rely on this high-quality intermediate for its consistent performance and purity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in heterocyclic chemistry for potential CNS and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the chloro-fluoro-phenylaniline structure contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Functional Material Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers requiring specific electronic properties.
• Dye and Pigment Intermediate: Acts as a diazo component or coupling agent in the production of high-performance, light-fast dyes and pigments.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for custom chemical synthesis services targeting complex, multi-step organic transformations.

Basic Information

Product Name	2-Chloro-4-Fluoro-6-Phenylaniline
CAS No.	1449008-12-1
Molecular Formula	C12H9ClFN
Molecular Weight	221.66 g/mol
Synonyms	2-Chloro-4-fluoro-6-phenylbenzenamine; 6-Phenyl-2-chloro-4-fluoroaniline; Benzenamine, 2-chloro-4-fluoro-6-phenyl-; 2-Chloro-4-fluoro-6-phenyl-1-aminobenzene; 2-Chloro-4-fluoro-6-phenyl-aniline; 2-Chloro-4-fluoro-6-phenylaniline (primary name); 2-Cl-4-F-6-Ph-aniline; 1449008-12-1 (CAS-based synonym)
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-6-Phenylaniline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for fine chemical and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be amber-colored or stored in a light-proof secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.