Description

(2S)-5-(Benzyloxy)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}(Methyl)Amino)-5-Oxopentanoic Acid is a sophisticated, optically active Fmoc-protected amino acid derivative designed for advanced synthetic chemistry. This compound serves as a critical, high-purity building block for the controlled synthesis of complex peptides and peptidomimetics, enabling precise molecular assembly. It is primarily utilized by research institutions and pharmaceutical development teams engaged in drug discovery, proteomics research, and the production of specialized bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid reagent for the sequential assembly of custom peptide sequences.
• Pharmaceutical Intermediate: In the research and development of novel therapeutic peptides and protein-based drugs.
• Bioconjugation: For the site-specific modification of proteins, antibodies, or other biomolecules to create conjugates for diagnostics or targeted therapies.
• Chemical Biology Probes: Synthesis of labeled or tagged peptide probes used to study protein-protein interactions and enzyme function.
• Peptidomimetic Development: Building block for creating non-natural peptide analogs with enhanced stability or biological activity.
• Academic & Industrial R&D: Fundamental research in organic synthesis, medicinal chemistry, and material science.

Basic Information

Product Name	(2S)-5-(Benzyloxy)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}(Methyl)Amino)-5-Oxopentanoic Acid
CAS No.	1448903-45-4
Molecular Formula	C28H27NO6
Molecular Weight	473.52 g/mol
Synonyms	Fmoc-N-Me-Asp(OBzl)-OH; Fmoc-N-methyl-L-aspartic acid 4-benzyl ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-aspartic acid 4-benzyl ester; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl](methyl)amino]-4-(benzyloxy)-4-oxobutanoic acid; Fmoc-N-methyl-Asp(OBzl)-OH; Nα-Fmoc-Nα-methyl-L-aspartic acid β-benzyl ester; N-Fmoc-N-methyl-L-aspartic acid 4-benzyl ester
EINECS	Contact for details

Quality Control

Our (2S)-5-(Benzyloxy)-2-({[(9H-Fluoren-9-Yl)Methoxy]Carbonyl}(Methyl)Amino)-5-Oxopentanoic Acid is manufactured under controlled conditions to ensure the high purity and consistency required for sensitive synthetic applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric excess. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.