Description

Zuclopenthixol Decanoate Dihydrochloride CAS NO 1448876-93-4 is a high-purity active pharmaceutical ingredient (API) belonging to the thioxanthene class of neuroleptic agents. This compound is a long-acting ester derivative, valued for its critical role in the formulation of sustained-release injectable antipsychotic medications. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of treatments for psychiatric disorders, ensuring consistent therapeutic delivery and patient compliance.

Application

• Primary API in Long-Acting Injectable (LAI) Antipsychotics: The principal application is as the active ingredient in depot injection formulations for the management of schizophrenia and other psychotic disorders.
• Pharmaceutical R&D: Serves as a key reference standard and starting material in the research and development of novel neuropsychiatric therapeutics and drug delivery systems.
• Generic Drug Manufacturing: Essential for the production of generic versions of established zuclopenthixol decanoate-based medications, supporting global healthcare access.
• Clinical Trial Material (CTM): Supplied under strict quality protocols as a critical component for clinical studies evaluating dosage, efficacy, and safety profiles.
• Veterinary Pharmaceutical Applications: Potential use in veterinary medicine for behavioral management in animals, subject to appropriate regulatory pathways.

Basic Information

Product Name	Zuclopenthixol Decanoate Dihydrochloride
CAS No.	1448876-93-4
Molecular Formula	C₃₂H₄₄Cl₂N₂O₂S
Molecular Weight	615.67 g/mol
Synonyms	Zuclopenthixol Decanoate Dihydrochloride; Zuclopenthixol Decanoate HCl; Cis(Z)-Clopenthixol Decanoate Dihydrochloride; (Z)-Clopenthixol Decanoate Dihydrochloride; (Z)-2-[4-[3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl]piperazin-1-yl]ethyl decanoate dihydrochloride; NSC 526046; Clopixol Depot (as salt form); Zuclopenthixol decanoate hydrochloride
EINECS	Contact for details

Quality Control

Our Zuclopenthixol Decanoate Dihydrochloride is manufactured and controlled under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and control of specified impurities, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, purity, and compliance with relevant ICH guidelines and customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.