Description

tert-Butyl 4-(Pyrimidin-4-Ylamino)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core protected by a Boc (tert-butoxycarbonyl) group and functionalized with a pyrimidin-4-ylamino moiety. This compound is crucial for medicinal chemistry research and development, serving as a key building block in the synthesis of novel drug candidates. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing targeted therapies, particularly in oncology and CNS (Central Nervous System) areas.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop novel therapeutic agents.
• Chemical Biology Probes: Serves as a precursor for creating molecular probes to study biological pathways and protein functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Library Synthesis: Used in the generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	tert-Butyl 4-(Pyrimidin-4-Ylamino)Piperidine-1-Carboxylate
CAS No.	1448854-95-2
Molecular Formula	C14H22N4O2
Molecular Weight	278.35 g/mol
Synonyms	1-Boc-4-(pyrimidin-4-ylamino)piperidine; 4-(Pyrimidin-4-ylamino)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-[(pyrimidin-4-yl)amino]piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(pyrimidin-4-ylamino)piperidine; 4-Aminopyrimidine piperidine Boc derivative; CAS 1448854-95-2
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Pyrimidin-4-Ylamino)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.