Description

3-(2-Fluorophenyl)-5H,6H,7H,8H-[1,2,4]Triazolo[4,3-A]Pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrimidine class of heterocyclic compounds. Its core value lies in serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. This compound is essential for research and development chemists and manufacturers in the global pharmaceutical, agrochemical, and life science industries seeking to develop new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used as a core scaffold for developing new herbicides, fungicides, and insecticides with enhanced activity.
• Chemical Biology Probe: Serves as a valuable tool compound for studying enzyme inhibition and biological pathway modulation in academic and industrial research.
• Material Science: Potential building block for creating specialty polymers or organic electronic materials due to its fused heterocyclic structure.
• Contract Research & Development (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client projects.

Basic Information

Item	Details
Product Name	3-(2-Fluorophenyl)-5H,6H,7H,8H-[1,2,4]Triazolo[4,3-A]Pyrimidine
CAS No.	1448854-89-4
Molecular Formula	C12H11FN4
Molecular Weight	230.24 g/mol
Synonyms	3-(2-Fluorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidine; 1448854-89-4; 3-(2-Fluorophenyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrimidine; 3-(2-Fluorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidine; 5,6,7,8-Tetrahydro-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-a]pyrimidine
EINECS	Contact for details

Quality Control

Our 3-(2-Fluorophenyl)-5H,6H,7H,8H-[1,2,4]Triazolo[4,3-A]Pyrimidine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.