Description

(1R*,4R*)-1-n-(Pyrimidin-2-Yl)Cyclohexane-1,4-Diamine Dihydrochloride is a high-purity, stereochemically defined diamine derivative, primarily utilized as a critical pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of complex molecules, enabling the development of targeted therapeutics. This compound is essential for research and development chemists in the pharmaceutical, biotechnology, and fine chemical industries, particularly for projects involving kinase inhibitors, antiviral agents, and other small-molecule drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase-targeted therapies.
• Biochemical Research: Used as a precursor or ligand in medicinal chemistry research for structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules requiring a rigid, bicyclic diamine scaffold.
• Catalyst Development: Potential use as a ligand in asymmetric catalysis for the production of enantiomerically pure compounds.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(1R*,4R*)-1-n-(Pyrimidin-2-Yl)Cyclohexane-1,4-Diamine Dihydrochloride
CAS No.	1448854-77-0
Molecular Formula	C10H18Cl2N4
Molecular Weight	265.18 g/mol
Synonyms	(1R*,4R*)-1-(Pyrimidin-2-yl)cyclohexane-1,4-diamine dihydrochloride; (1R,4R)-1-(Pyrimidin-2-yl)cyclohexane-1,4-diamine dihydrochloride; 1-(Pyrimidin-2-yl)cyclohexane-1,4-diamine dihydrochloride (racemic); 1,4-Diamino-1-(2-pyrimidinyl)cyclohexane dihydrochloride; 1448854-77-0; UNII-2Z7Q3Q2K4T; 2Z7Q3Q2K4T; (1R,4R)-1-(2-Pyrimidinyl)-1,4-cyclohexanediamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (1R*,4R*)-1-n-(Pyrimidin-2-Yl)Cyclohexane-1,4-Diamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via spectroscopic methods. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.