Description

3-(3-Fluorophenyl)-5H,6H,7H,8H-[1,2,4]Triazolo[4,3-A]Pyrimidine CAS NO 1448854-61-2 is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and modulators of neurological targets.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Used in the development of labeled compounds for target identification and validation studies.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and development.

Basic Information

Product Name	3-(3-Fluorophenyl)-5H,6H,7H,8H-[1,2,4]Triazolo[4,3-A]Pyrimidine
CAS No.	1448854-61-2
Molecular Formula	C12H11FN4
Molecular Weight	230.24 g/mol
Synonyms	3-(3-Fluorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidine; 3-(3-Fluorophenyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrimidine; 1448854-61-2; 3-(3-Fluorophenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrimidine; 3-(3-Fluorophenyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrimidine; 3-(3-Fluorophenyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrimidine
EINECS	Contact for details

Quality Control

Our 3-(3-Fluorophenyl)-5H,6H,7H,8H-[1,2,4]Triazolo[4,3-A]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.