Description

tert-Butyl (3R)-3-[(6-Methylpyrimidin-4-yl)amino]pyrrolidine-1-carboxylate is a high-purity chiral building block and Boc-protected intermediate of significant value in modern synthetic chemistry. Its core value lies in providing a stereochemically defined pyrrolidine scaffold for the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Serves as a crucial building block for creating advanced crop protection agents and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Biology Research: Employed as a probe or scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.

Basic Information

Product Name	tert-Butyl (3R)-3-[(6-Methylpyrimidin-4-yl)amino]pyrrolidine-1-carboxylate
CAS No.	1448850-61-0
Molecular Formula	C14H22N4O2
Molecular Weight	278.35 g/mol
Synonyms	1-Boc-3-[(6-methylpyrimidin-4-yl)amino]-(3R)-pyrrolidine; (R)-tert-Butyl 3-((6-methylpyrimidin-4-yl)amino)pyrrolidine-1-carboxylate; (3R)-1-(tert-Butoxycarbonyl)-3-[(6-methyl-4-pyrimidinyl)amino]pyrrolidine; tert-Butyl (R)-3-((6-methylpyrimidin-4-yl)amino)pyrrolidine-1-carboxylate; 1448850-61-0; (R)-1-Boc-3-((6-methylpyrimidin-4-yl)amino)pyrrolidine; Boc-(R)-3-((6-methylpyrimidin-4-yl)amino)pyrrolidine
EINECS	Contact for details

Quality Control

Our tert-Butyl (3R)-3-[(6-Methylpyrimidin-4-yl)amino]pyrrolidine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed HPLC, NMR, and chiral assay data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.