Description

6-Methyl-n-[(3R)-Pyrrolidin-3-Yl]Pyrimidin-4-Amine Dihydrochloride is a high-purity, chiral organic salt of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or building block for the creation of novel, biologically active molecules. It is primarily utilized by medicinal chemists and process development scientists within the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Ligand Synthesis: Can be utilized in the preparation of specialized ligands for catalysis or biochemical assays.
• Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Item	Detail
Product Name	6-Methyl-n-[(3R)-Pyrrolidin-3-Yl]Pyrimidin-4-Amine Dihydrochloride
CAS No.	1448850-52-9
Molecular Formula	C9H17Cl2N5
Molecular Weight	266.17 g/mol
Synonyms	(3R)-3-[(6-Methylpyrimidin-4-yl)amino]pyrrolidine dihydrochloride; 6-Methyl-N-[(3R)-pyrrolidin-3-yl]pyrimidin-4-amine dihydrochloride; (R)-3-((6-Methylpyrimidin-4-yl)amino)pyrrolidine hydrochloride (1:2); 4-Amino-6-methyl-N-[(3R)-3-pyrrolidinyl]pyrimidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 6-Methyl-n-[(3R)-Pyrrolidin-3-Yl]Pyrimidin-4-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment and allowed to reach ambient temperature before opening to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.