Description

6-Heptenoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-2-Methyl- is a specialized, high-purity building block designed for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel pharmaceuticals and bioactive molecules. Its primary value lies in its role as a protected amino acid derivative, enabling the controlled synthesis of complex peptides and peptidomimetics under standard Fmoc solid-phase peptide synthesis (SPPS) conditions. This makes it an essential material for pharmaceutical R&D, biotechnology, and advanced material science applications where structural integrity and purity are paramount.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate in Fmoc-based strategies for constructing complex peptide sequences.
• Pharmaceutical Research & Development: Used as a building block for synthesizing novel drug candidates, especially peptidomimetics and constrained peptides.
• Bioconjugation: Serves as a linker or functional handle for attaching peptides to other molecules, surfaces, or nanoparticles.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new biologically active compounds.
• Proteomics & Biochemical Tool Development: Used to create modified peptides for studying protein-protein interactions and enzyme mechanisms.
• Material Science: Potential precursor for designing peptide-based polymers and smart biomaterials.

Basic Information

Product Name	6-Heptenoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-2-Methyl-
CAS No.	1448775-45-8
Molecular Formula	C23H25NO4
Molecular Weight	379.45 g/mol
Synonyms	Fmoc-2-Amino-2-methyl-6-heptenoic acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-methyl-6-heptenoic acid; N-Fmoc-2-amino-2-methyl-6-heptenoic acid; 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methylhept-6-enoic acid; Fmoc-Amino-2-methyl-6-heptenoic Acid; Fmoc-MeAla(6-en)-OH (common abbreviation); Nα-Fmoc-2-methyl-6-heptenoic acid; Protected 2-methyl-6-heptenoic acid
EINECS	Contact for details

Quality Control

Every batch of 6-Heptenoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-2-Methyl- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with exacting purity standards suitable for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to minimize moisture uptake. For short-term use (up to one month), storage at 2-8°C in a desiccator is acceptable.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.