Description

5H-Pyrrolo[3,2-D]Pyrimidine, 4-Chloro-7-Iodo- is a high-value halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process R&D teams in the life sciences sector for the synthesis of novel active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies due to its versatile pyrrolopyrimidine core.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and cellular pathways.
• Agrochemical Research: Serves as a building block for developing novel crop protection agents and pesticides.
• Material Science: Potential precursor for organic electronic materials and ligands in catalytic systems.

Basic Information

Item	Details
Product Name	5H-Pyrrolo[3,2-D]Pyrimidine, 4-Chloro-7-Iodo-
CAS No.	1448695-71-3
Molecular Formula	C6H3ClIN3
Molecular Weight	279.47 g/mol
Synonyms	4-Chloro-7-iodo-5H-pyrrolo[3,2-d]pyrimidine; 4-Chloro-7-iodo-7H-pyrrolo[3,2-d]pyrimidine; 7-Iodo-4-chloro-5H-pyrrolo[3,2-d]pyrimidine; 4-Chloro-7-iodopyrrolo[3,2-d]pyrimidine; Halogenated Pyrrolopyrimidine; CAS 1448695-71-3
EINECS	Contact for details

Quality Control

Our 5H-Pyrrolo[3,2-D]Pyrimidine, 4-Chloro-7-Iodo- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.