Description

2-Bromo-4-Fluoro-6-Iodoaniline is a high-purity halogenated aniline derivative, a key building block in advanced organic synthesis. Its unique multi-halogen substitution pattern makes it an indispensable intermediate for creating complex molecular architectures with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a key building block for developing novel herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and cross-coupling reactions (e.g., Buchwald-Hartwig amination).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional materials requiring halogenated aromatic cores.
• Chemical Biology Probes: Acts as a versatile scaffold for creating fluorescent tags, photoaffinity labels, and other molecular probes for biological research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-4-Fluoro-6-Iodoaniline
CAS No.	1447606-71-4
Molecular Formula	C6H4BrFIN
Molecular Weight	315.91 g/mol
Synonyms	1-Amino-2-bromo-4-fluoro-6-iodobenzene; 2-Bromo-4-fluoro-6-iodobenzenamine; Benzenamine, 2-bromo-4-fluoro-6-iodo-; 6-Iodo-2-bromo-4-fluoroaniline; 4-Fluoro-2-bromo-6-iodoaniline; 2-Bromo-4-fluoro-6-iodophenylamine; (2-Bromo-4-fluoro-6-iodophenyl)amine
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-6-Iodoaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, impurity profiles, and physical characteristics. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to prevent moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.