Description

Fmoc-Hyp(Oet)-Oh CAS NO 1446478-31-4 is a protected amino acid derivative, specifically an Fmoc-protected hydroxyproline with an O-ethyl ether side chain, essential for advanced peptide synthesis. This building block is critical for researchers and manufacturers requiring precise control over peptide structure and function, particularly for introducing post-translational modifications. It is primarily utilized by pharmaceutical R&D teams, biotech companies, and CROs engaged in the development of therapeutic peptides, peptidomimetics, and complex biomolecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the Fmoc-strategy assembly of complex peptide sequences.
• Therapeutic Peptide Development: Used in the research and production of peptide-based drugs targeting various diseases.
• Collagen-Mimetic Peptides: Essential for synthesizing peptides that mimic the structure of collagen, important for studies in tissue engineering and wound healing.
• Peptidomimetic & Macrocycle Synthesis: Serves as a constrained scaffold for creating stable, drug-like molecules with improved pharmacokinetic properties.
• Bioconjugation & Probe Development: Facilitates the site-specific incorporation of modified proline residues for labeling or functionalization.
• Academic & Industrial Research: A vital reagent for biochemical studies exploring protein-protein interactions and enzyme specificity.

Basic Information

Product Name	Fmoc-Hyp(Oet)-Oh
CAS No.	1446478-31-4
Molecular Formula	C23H25NO6
Molecular Weight	411.45 g/mol
Synonyms	Fmoc-Hyp(Oet)-OH; Fmoc-O-ethyl-hydroxyproline; Fmoc-trans-4-(Ethoxy)-L-proline; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-(ethoxy)-L-proline; (2S,4R)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-ethoxypyrrolidine-2-carboxylic acid; Fmoc-4-(OEt)-Hyp-OH; Fmoc-L-Hyp(OEt)-OH; Protected Hydroxyproline Derivative
EINECS	Contact for details

Quality Control

Every batch of Fmoc-Hyp(Oet)-Oh is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and related substances. Our quality commitment aligns with the standards required for GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccants and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.