Description

2-Ethoxy-4-Fluoro-5-Nitroaniline is a high-purity, specialized aromatic amine derivative of significant industrial importance. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in fine chemical synthesis. It is primarily sought by manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates.
• Agrochemical Synthesis: Building block for developing advanced herbicides, pesticides, and fungicides containing fluoro-nitroaniline motifs.
• Dye and Pigment Manufacturing: Intermediate for producing specialized azo dyes and colorants with enhanced light-fastness properties.
• Material Science Research: Used in the development of novel polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating complex aromatic amines.
• Chemical Research & Development: Essential reagent for medicinal chemistry and process chemistry research in both academic and industrial settings.

Basic Information

Product Name	2-Ethoxy-4-Fluoro-5-Nitroaniline
CAS No.	1446413-77-9
Molecular Formula	C8H9FN2O3
Molecular Weight	200.17 g/mol
Synonyms	5-Nitro-2-ethoxy-4-fluoroaniline; 4-Fluoro-2-ethoxy-5-nitroaniline; 2-Ethoxy-4-fluoro-5-nitrobenzenamine; Benzenamine, 2-ethoxy-4-fluoro-5-nitro-; 4-Fluoro-5-nitro-2-ethoxyaniline; 2-Amino-5-nitro-1-ethoxy-4-fluorobenzene; 1-Ethoxy-2-amino-4-fluoro-5-nitrobenzene
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-4-Fluoro-5-Nitroaniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent lot-to-lot quality. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.