Description

3-Bromo-6-Nitro-2-(Trifluoromethyl)Aniline, also known as 3-Bromo-6-Nitro-Alpha,Alpha,α-Trifluoro-o-Toluidine, is a high-value, multi-functional aromatic amine intermediate. Its unique structure, featuring bromo, nitro, and trifluoromethyl substituents, makes it a critical building block for synthesizing complex molecules with tailored electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Serves as a core building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and nitro groups.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and advanced polymers where electron-withdrawing groups are required to tune material properties.
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing specialized azo dyes and pigments with enhanced lightfastness and color properties.
• Cross-Coupling Reactions: The bromo substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct more complex biaryl structures.
• Chemical Research & Development: A versatile reagent for exploring new synthetic methodologies and creating compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	3-Bromo-6-Nitro-2-(Trifluoromethyl)Aniline
CAS No.	1445995-76-5
Molecular Formula	C7H4BrF3N2O2
Molecular Weight	285.02 g/mol
Synonyms	3-Bromo-6-Nitro-Alpha,Alpha,α-Trifluoro-o-Toluidine; 2-Amino-3-bromo-6-nitrobenzotrifluoride; 2-Trifluoromethyl-3-bromo-6-nitroaniline; 3-Bromo-6-nitro-2-(trifluoromethyl)benzenamine; Benzenamine, 3-bromo-6-nitro-2-(trifluoromethyl)-; o-Toluidine, 3-bromo-6-nitro-alpha,alpha,α-trifluoro-; 3-Br-6-NO2-2-CF3-Aniline
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-6-Nitro-2-(Trifluoromethyl)Aniline is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.