Description

6-Bromo-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrimidine class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted therapeutic effects. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly for oncology and inflammatory diseases.
• Kinase Inhibitor Scaffold: Serves as a core structural motif for designing and synthesizing potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery programs.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one
CAS No.	1443677-11-9
Molecular Formula	C7H6BrN3O
Molecular Weight	228.05 g/mol
Synonyms	6-Bromo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-2-one; 6-Bromo-3,4-dihydro-1H-pyrido[2,3-d]pyrimidin-2-one; 1443677-11-9; 6-Bromotetrahydropyrido[2,3-d]pyrimidin-2(1H)-one; 6-Bromo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidin-2-one; 6-Bromo-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one; 6-Bromo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 6-Bromo-3,4-dihydropyrido[2,3-d]pyrimidin-2(1H)-one is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of pharmaceutical R&D. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable and support regulatory filings with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.