Description

6-Chloro-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in kinase inhibitor research. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted therapeutic molecules, especially protein kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Serves as a core structure for developing selective enzyme modulators and probes for biological pathway analysis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	6-Chloro-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	1443291-37-9
Molecular Formula	C7H5ClN4
Molecular Weight	180.59 g/mol
Synonyms	1-Methyl-6-chloro-1H-pyrazolo[3,4-d]pyrimidine; 6-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 6-chloro-1-methyl-; 6-Chloro-1-methylpyrazolo[3,4-d]pyrimidine; 1443291-37-9; 6-Chloro-1-methyl-7H-pyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 6-Chloro-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.