Description

4,6-Dichloro-5-(difluoromethyl)pyrimidine is a high-value, multi-functional pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring reactive chlorine atoms and a difluoromethyl group, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and production of active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine core.
• Material Science Research: Serves as a precursor for developing specialty chemicals, liquid crystals, and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: An essential starting material for fine chemical companies offering bespoke synthesis services.

Basic Information

Product Name	4,6-Dichloro-5-(difluoromethyl)pyrimidine
CAS No.	1443290-45-6
Molecular Formula	C5H2Cl2F2N2
Molecular Weight	198.98 g/mol
Synonyms	5-(Difluoromethyl)-4,6-dichloropyrimidine; 4,6-Dichloro-5-difluoromethylpyrimidine; Pyrimidine, 4,6-dichloro-5-(difluoromethyl)-; 1443290-45-6
EINECS	Contact for details

Quality Control

Our production of 4,6-Dichloro-5-(difluoromethyl)pyrimidine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for manufacturing critical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.