Description

6-Chloro-5-Cyclopropyl-Pyrazolo[1,5-A]Pyrimidine-7-Carboxylic Acid is a high-purity, functionalized pyrazolopyrimidine derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its precise molecular architecture, which provides a versatile scaffold for constructing novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to develop new small-molecule drugs and crop protection agents.

Application

This specialized intermediate is designed for sophisticated synthesis applications, primarily in life sciences research and development.

• Pharmaceutical Intermediate: A key building block for the synthesis of novel kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new fungicides and herbicides, leveraging its heterocyclic core.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses serving the pharmaceutical and biotechnology sectors.
• Academic & Institutional Research: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Item	Details
Product Name	6-Chloro-5-Cyclopropyl-Pyrazolo[1,5-A]Pyrimidine-7-Carboxylic Acid
CAS No.	1443279-05-7
Molecular Formula	C10H7ClN4O2
Molecular Weight	250.64 g/mol
Synonyms	6-Chloro-5-cyclopropylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid; 5-Cyclopropyl-6-chloropyrazolo[1,5-a]pyrimidine-7-carboxylic acid; 1443279-05-7; 6-Chloro-5-cyclopropyl-7-pyrazolo[1,5-a]pyrimidinecarboxylic acid; 7-Carboxy-6-chloro-5-cyclopropylpyrazolo[1,5-a]pyrimidine; 6-Chloro-5-cyclopropyl-pyrazolo[1,5-a]pyrimidine-7-carboxylic acid; 5-Cyclopropyl-6-chloro-7-carboxypyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-5-Cyclopropyl-Pyrazolo[1,5-A]Pyrimidine-7-Carboxylic Acid adheres to stringent quality management systems to ensure batch-to-batch consistency and reliability for your critical syntheses. All materials undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support compliance with relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is stable under these conditions but should be kept away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.