Description

6-Bromo-2-Fluoro-3-Hydroxyaniline is a high-purity, multi-functional aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated and hydroxylated structure makes it an invaluable intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging its halogenated aniline core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced polymers, dyes, and functional materials requiring specific electronic or steric properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up production under cGMP conditions for clinical trials.

Basic Information

Product Name	6-Bromo-2-Fluoro-3-Hydroxyaniline
CAS No.	1443107-59-2
Molecular Formula	C6H5BrFNO
Molecular Weight	206.01 g/mol
Synonyms	3-Amino-6-bromo-2-fluorophenol; 2-Fluoro-6-bromo-3-aminophenol; 6-Bromo-2-fluoro-3-aminophenol; 2-Fluoro-6-bromobenzene-1,3-diamine (tautomer); 1-Amino-2-bromo-5-fluoro-3-hydroxybenzene; 6-Bromo-2-fluoro-3-hydroxybenzenamine; Benzenamine, 6-bromo-2-fluoro-3-hydroxy-
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Fluoro-3-Hydroxyaniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material suitable for use under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.