Description

3-Bromo-2-Hydroxy-5-[(Trifluoromethyl)Sulphonyl]Aniline, 3-Amino-5-Bromo-4-Hydroxyphenyl Trifluoromethyl Sulphone is a high-value, multi-functional aromatic building block featuring a unique combination of bromo, hydroxy, amino, and trifluoromethylsulphonyl substituents. This compound is critical for advanced organic synthesis, enabling the introduction of key functional groups that modulate the electronic and steric properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethylsulphonyl group enhances biological activity and environmental stability.
• Material Science Research: Acts as a monomer or functionalizing agent for creating specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Bromo-2-Hydroxy-5-[(Trifluoromethyl)Sulphonyl]Aniline, 3-Amino-5-Bromo-4-Hydroxyphenyl Trifluoromethyl Sulphone
CAS No.	1440535-13-6
Molecular Formula	C7H6BrF3NO3S
Molecular Weight	321.09 g/mol
Synonyms	3-Amino-5-bromo-4-hydroxyphenyl trifluoromethyl sulphone; 3-Bromo-2-hydroxy-5-[(trifluoromethyl)sulfonyl]aniline; 5-Bromo-2-amino-4-hydroxy-α,α,α-trifluorotoluene-4'-sulfone; 4-Hydroxy-3-amino-5-bromophenyl trifluoromethyl sulfone; 3-Bromo-2-hydroxy-5-(trifluoromethylsulfonyl)aniline; 3-Amino-5-bromo-4-hydroxybenzenesulfonyl fluoride, trifluoromethyl derivative; 1440535-13-6
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Hydroxy-5-[(Trifluoromethyl)Sulphonyl]Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.