Description

7,8-Dihydro-5H-Pyrido[4,3-D]Pyrimidine-6-Carboxylic Acid Benzyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its fused pyridopyrimidine scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries for the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex heterocyclic compounds for drug discovery programs.
• Kinase Inhibitor Development: Used in the research and production of potential kinase inhibitors, a major class of targeted cancer therapies.
• Chemical Biology Research: Employed as a scaffold or probe in biochemical assays to study enzyme function and cellular pathways.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Academic Research: Used in university and institutional labs for methodological development and the exploration of new chemical spaces.

Basic Information

Product Name	7,8-Dihydro-5H-Pyrido[4,3-D]Pyrimidine-6-Carboxylic Acid Benzyl Ester
CAS No.	1440526-49-7
Molecular Formula	C15H15N3O2
Molecular Weight	269.30 g/mol
Synonyms	Benzyl 7,8-dihydro-5H-pyrido[4,3-d]pyrimidine-6-carboxylate; 5H-Pyrido[4,3-d]pyrimidine-6-carboxylic acid, 7,8-dihydro-, phenylmethyl ester; 1440526-49-7; Pyrido[4,3-d]pyrimidine-6-carboxylic acid benzyl ester, 7,8-dihydro-; Benzyl 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-6-carboxylate (tautomeric form); 6-(Benzyloxycarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 7,8-Dihydro-5H-Pyrido[4,3-D]Pyrimidine-6-Carboxylic Acid Benzyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.