Description

5-(1,3-Benzodioxol-5-Yl)-n-[(3,5-Dichlorophenyl)Methyl]-4-Pyrimidinamine Hydrochloride is a high-purity, synthetic organic compound primarily utilized as a key pharmaceutical intermediate or research chemical. Its molecular structure, featuring a benzodioxole and dichlorophenyl moiety, makes it a valuable building block in medicinal chemistry for the development of novel therapeutic agents. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential active pharmaceutical ingredients (APIs) for various therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold or building block in structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Research: Employed in the study of enzyme inhibition or receptor binding assays due to its specific heterocyclic structure.
• Reference Standard: Functions as an analytical standard for quality control, method development, and regulatory submissions in pharmaceutical manufacturing.
• Process Chemistry: Utilized in route scouting and scale-up development for efficient and cost-effective API synthesis.

Basic Information

Product Name	5-(1,3-Benzodioxol-5-Yl)-n-[(3,5-Dichlorophenyl)Methyl]-4-Pyrimidinamine Hydrochloride
CAS No.	1440251-53-5
Molecular Formula	C19H15Cl2N3O2 • HCl
Molecular Weight	421.71 g/mol
Synonyms	4-Pyrimidinamine, 5-(1,3-benzodioxol-5-yl)-N-[(3,5-dichlorophenyl)methyl]-, hydrochloride (1:1); 5-(Benzo[d][1,3]dioxol-5-yl)-N-((3,5-dichlorophenyl)methyl)pyrimidin-4-amine hydrochloride; 1440251-53-5; UNII-9J8C6T8Q3P; 9J8C6T8Q3P
EINECS	Contact for details

Quality Control

Our 5-(1,3-Benzodioxol-5-Yl)-n-[(3,5-Dichlorophenyl)Methyl]-4-Pyrimidinamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.