Description

2-(3-(Trifluoromethyl)Phenyl)Propan-2-Amine Hydrochloride is a high-purity, fluorinated aromatic amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the trifluoromethyl group's metabolic stability and lipophilicity with the reactive amine functionality, making it indispensable for creating novel molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and intermediates. CAS No. 1439900-32-9 identifies this specific chemical entity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and insecticides where the CF₃ group enhances biological activity and environmental persistence.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate for synthesizing fluorinated polymers and advanced organic electronic materials.
• Chemical Biology: Useful as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for client-specific molecule development.

Basic Information

Product Name	2-(3-(Trifluoromethyl)Phenyl)Propan-2-Amine Hydrochloride
CAS No.	1439900-32-9
Molecular Formula	C₁₀H₁₁F₃N•HCl
Molecular Weight	241.66 g/mol (Free base: 205.20 g/mol)
Synonyms	1-(3-(Trifluoromethyl)phenyl)-2-aminopropane Hydrochloride; α,α-Dimethyl-3-(trifluoromethyl)benzeneethanamine Hydrochloride; 2-Amino-2-methyl-1-[3-(trifluoromethyl)phenyl]propane Hydrochloride; 3-(Trifluoromethyl)amphetamine Hydrochloride; 1-(3-Trifluoromethylphenyl)-2-aminopropane HCl; 2-(3-Trifluoromethylphenyl)isopropylamine HCl
EINECS	Contact for details

Quality Control

Our 2-(3-(Trifluoromethyl)Phenyl)Propan-2-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with high-grade standards for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 102.0% (as hydrochloride salt)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.