Description

6-[2-Oxo-Tetrahydropyrimidin-1(2H)-Yl]Pyrimidine-4-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in medicinal chemistry programs targeting enzyme inhibition. Research and development teams in the pharmaceutical, agrochemical, and fine chemical industries require this precise molecule for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new chemical entities (NCEs) for drug discovery, particularly for kinase inhibitors and other enzyme-targeted therapies.
• Medicinal Chemistry Research: Used as a versatile building block for constructing fused heterocyclic scaffolds in structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a precursor in the synthesis of novel active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value compounds.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	6-[2-Oxo-Tetrahydropyrimidin-1(2H)-Yl]Pyrimidine-4-Carboxylic Acid
CAS No.	1439896-56-6
Molecular Formula	C9H8N4O3
Molecular Weight	220.19 g/mol
Synonyms	1-(4-Carboxypyrimidin-6-yl)tetrahydropyrimidin-2(1H)-one; 6-(2-Oxotetrahydropyrimidin-1(2H)-yl)pyrimidine-4-carboxylic acid; 6-(2-Oxo-1,2,3,4-tetrahydropyrimidin-1-yl)pyrimidine-4-carboxylic acid; Pyrimidine-4-carboxylic acid, 6-[2-oxo-1(2H)-tetrahydropyrimidinyl]-; 1439896-56-6; Building Block 1439896-56-6; Heterocyclic Carboxylic Acid Intermediate
EINECS	Contact for details

Quality Control

Our 6-[2-Oxo-Tetrahydropyrimidin-1(2H)-Yl]Pyrimidine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.