Description

4-(2-Chloro-6-((1-(Cyclopropylmethyl)Piperidin-4-Yl)Methyl)Thieno[3,2-D]Pyrimidin-4-Yl)Morpholine is a high-purity, advanced pharmaceutical intermediate belonging to the thienopyrimidine class of heterocyclic compounds. This compound matters for its critical role as a key building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology and kinase inhibitor research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precisely characterized material to ensure the integrity and reproducibility of their drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs), especially kinase inhibitors.
• Oncology Research: Used as a core scaffold in the design and development of novel anti-cancer compounds targeting specific cellular pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of drug candidates.
• Biochemical Tool Compound: Utilized in vitro and in vivo to study and validate biological targets and mechanisms of action.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for cutting-edge research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	4-(2-Chloro-6-((1-(Cyclopropylmethyl)Piperidin-4-Yl)Methyl)Thieno[3,2-D]Pyrimidin-4-Yl)Morpholine
CAS No.	1439824-03-9
Molecular Formula	C20H27ClN4OS
Molecular Weight	406.97 g/mol
Synonyms	4-(2-Chloro-6-((1-(cyclopropylmethyl)piperidin-4-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine; Thieno[3,2-d]pyrimidine derivative CAS 1439824-03-9; 4-Morpholino-2-chloro-6-((1-(cyclopropylmethyl)piperidin-4-yl)methyl)thieno[3,2-d]pyrimidine; 2-Chloro-6-((1-(cyclopropylmethyl)-4-piperidinyl)methyl)-4-(4-morpholinyl)thieno[3,2-d]pyrimidine; Kinase inhibitor intermediate 1439824-03-9
EINECS	Contact for details

Quality Control

Our 4-(2-Chloro-6-((1-(Cyclopropylmethyl)Piperidin-4-Yl)Methyl)Thieno[3,2-D]Pyrimidin-4-Yl)Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and conformity to client specifications. Certificates of Analysis (COA) detailing all test results are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.