Description

5-Bromo-n-(Oxetan-3-Yl)Pyrimidin-2-Amine is a high-purity, advanced pharmaceutical intermediate featuring a pyrimidine core functionalized with a bromo substituent and an oxetane-containing amine. This compound is valued for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of small-molecule drugs, particularly within oncology and targeted therapy research.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Synthesis: Used in constructing core scaffolds for potential kinase inhibitors, a major class of oncology drugs.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs.
• Bioconjugation & Probe Development: The reactive bromo group allows for further functionalization, useful in creating chemical probes for biological studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	5-Bromo-n-(Oxetan-3-Yl)Pyrimidin-2-Amine
CAS No.	1439823-02-5
Molecular Formula	C7H8BrN3O
Molecular Weight	230.06 g/mol
Synonyms	5-Bromo-N-(oxetan-3-yl)pyrimidin-2-amine; 2-Pyrimidinamine, 5-bromo-N-(oxetan-3-yl)-; 5-Bromo-2-(oxetan-3-ylamino)pyrimidine; 1439823-02-5; Oxetan-3-yl-(5-bromopyrimidin-2-yl)amine; 5-Bromo-N-oxetan-3-yl-pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-(Oxetan-3-Yl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.