Description

2-Chloro-4-Morpholinopyrido[2,3-D]Pyrimidine-7-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with significant value in modern drug discovery and development. This heterocyclic carboxylic acid derivative serves as a critical building block for synthesizing targeted kinase inhibitors and other biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel oncology and anti-inflammatory therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small-molecule kinase inhibitors targeting various disease pathways.
• Oncology Research: Used in the development of novel anti-cancer agents, particularly those targeting specific protein kinases involved in cell proliferation and survival.
• Medicinal Chemistry R&D: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme function and inhibition mechanisms.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and drug design.

Basic Information

Product Name	2-Chloro-4-Morpholinopyrido[2,3-D]Pyrimidine-7-Carboxylic Acid
CAS No.	1439818-90-2
Molecular Formula	C12H9ClN4O3
Molecular Weight	292.68 g/mol
Synonyms	2-Chloro-4-morpholin-4-ylpyrido[2,3-d]pyrimidine-7-carboxylic acid; 4-Morpholin-4-yl-2-chloropyrido[2,3-d]pyrimidine-7-carboxylic acid; 2-Chloro-4-(morpholin-4-yl)pyrido[2,3-d]pyrimidine-7-carboxylic acid; 2-Chloro-4-morpholinopyrido[2,3-d]pyrimidine-7-carboxylic acid; 1439818-90-2; Pyrido[2,3-d]pyrimidine-7-carboxylic acid, 2-chloro-4-morpholino-; 2-Chloro-4-morpholin-4-yl-7-pyrido[2,3-d]pyrimidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Morpholinopyrido[2,3-D]Pyrimidine-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.