Description

2,4-Difluoro-3-Iodoaniline is a high-value halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring iodine and fluorine substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluorine and iodine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in cross-coupling reactions (e.g., Suzuki, Sonogashira) and other catalytic processes.
• Material Science Research: Employed in the creation of organic electronic materials, such as semiconductors and liquid crystals, where halogenated aromatics tune optical and electronic properties.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for imaging and diagnostic applications due to the reactivity of the iodine atom for further functionalization.
• Custom Synthesis and Contract Manufacturing: A vital substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2,4-Difluoro-3-Iodoaniline
CAS No.	1437316-91-0
Molecular Formula	C6H4F2IN
Molecular Weight	254.99 g/mol
Synonyms	3-Iodo-2,4-difluoroaniline; 2,4-Difluoro-3-iodobenzenamine; Benzenamine, 2,4-difluoro-3-iodo-; 3-Iodo-2,4-difluoro-benzenamine; 2,4-Difluoro-3-iodo-phenylamine; 2,4-Difluoro-3-iodoaniline (primary); 3-Iodo-2,4-difluoroaniline (main); 2,4-DF-3-I-aniline
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-3-Iodoaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC-MS for impurity profiling. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.