Description

2-Chloro-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Hydrochloride is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in medicinal chemistry research targeting kinase inhibition and other therapeutic pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Employed in the construction of complex polyheterocyclic systems due to its reactive chloro and pyrimidine functionalities.
• Agrochemical Research: Potential intermediate in the development of novel active ingredients for crop protection products.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	2-Chloro-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Hydrochloride
CAS No.	1432795-17-9
Molecular Formula	C7H9ClN3·HCl
Molecular Weight	220.08 g/mol
Synonyms	2-Chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine HCl; 2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride; 2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine HCl; 2-Chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine monohydrochloride; 1432795-17-9; 2-Chloro-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride salt
EINECS	Contact for details

Quality Control

Our 2-Chloro-5,6,7,8-Tetrahydropyrido[3,4-D]Pyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.